4,312 research outputs found
Submicrometric Films of Surface-Attached Polymer Network with Temperature-Responsive Properties
Temperature-responsive properties of surface-attached
poly(N-isopropylacrylamide) (PNIPAM) network films with well-controlled
chemistry are investigated. The synthesis consists of cross-linking and
grafting preformed ene-reactive polymer chains through thiol--ene click
chemistry. The formation of surface-attached and cross-linked polymer films has
the advantage of being wellcontrolled without any caution of no-oxygen
atmosphere or addition of initiators. PNIPAM hydrogel films with same
cross-link density are synthesized on a wide range of thickness, from
nanometers to micrometers. The swelling-collapse transition with temperature is
studied by using ellipsometry, neutron reflectivity, and atomic force
microscopy as complementary surface-probing techniques. Sharp and high
amplitude temperature-induced phase transition is observed for all
submicrometric PNIPAM hydrogel films. For temperature above LCST,
surface-attached PNIPAM hydrogels collapse similarly but without complete
expulsion of water. For temperature below LCST, the swelling of PNIPAM
hydrogels depends on the film thickness. It is shown that the swelling is
strongly affected by the surface attachment for ultrathin films below 150
nm. For thicker films above 150 nm (to micrometers), surface-attached polymer
networks with the same cross-link density swell equally. The density profile of
the hydrogel films in the direction normal to the substrate is confronted with
in-plane topography of the free surface. It results that the free interface
width is much larger than the roughness of the hydrogel film, suggesting
pendant chains at the free surface.Comment: in Langmuir, American Chemical Society, 2015, LANGMUIR, 31 (42),
pp.11516-1152
Downsizing assessment of automotive Stirling engines
A 67 kW (90 hp) Stirling engine design, sized for use in a 1984 1440 kg (3170 lb) automobile was the focal point for developing automotive Stirling engine technology. Since recent trends are towards lighter vehicles, an assessment was made of the applicability of the Stirling technology being developed for smaller, lower power engines. Using both the Philips scaling laws and a Lewis Research Center (Lewis) Stirling engine performance code, dimensional and performance characteristics were determined for a 26 kW (35 hp) and a 37 kW (50 hp) engine for use in a nominal 907 kg (2000 lb) vehicle. Key engine elements were sized and stressed and mechanical layouts were made to ensure mechanical fit and integrity of the engines. Fuel economy estimates indicated that the Stirling engine would maintain a 30 to 45 percent fuel economy advantage comparable spark ignition and diesel powered vehicles in the 1984 period
Controls on development and diversity of Early Archean stromatolites
The ≈3,450-million-year-old Strelley Pool Formation in Western Australia contains a reef-like assembly of laminated sedimentary accretion structures (stromatolites) that have macroscale characteristics suggestive of biological influence. However, direct microscale evidence of biology—namely, organic microbial remains or biosedimentary fabrics—has to date eluded discovery in the extensively-recrystallized rocks. Recently-identified outcrops with relatively good textural preservation record microscale evidence of primary sedimentary processes, including some that indicate probable microbial mat formation. Furthermore, we find relict fabrics and organic layers that covary with stromatolite morphology, linking morphologic diversity to changes in sedimentation, seafloor mineral precipitation, and inferred microbial mat development. Thus, the most direct and compelling signatures of life in the Strelley Pool Formation are those observed at the microscopic scale. By examining spatiotemporal changes in microscale characteristics it is possible not only to recognize the presence of probable microbial mats during stromatolite development, but also to infer aspects of the biological inputs to stromatolite morphogenesis. The persistence of an inferred biological signal through changing environmental circumstances and stromatolite types indicates that benthic microbial populations adapted to shifting environmental conditions in early oceans
OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency
Studies of the functional consequences of DCM-causing mutations have been limited to a few cases where patients with known mutations had heart transplants. To increase the number of potential tissue samples for direct investigation we performed whole exon sequencing of explanted heart muscle samples from 30 patients that had a diagnosis of familial dilated cardiomyopathy and screened for potentially disease-causing mutations in 58 HCM or DCM-related genes.We identified 5 potentially disease-causing OBSCN mutations in 4 samples; one sample had two OBSCN mutations and one mutation was judged to be not disease-related. Also identified were 6 truncating mutations in TTN, 3 mutations in MYH7, 2 in DSP and one each in TNNC1, TNNI3, MYOM1, VCL, GLA, PLB, TCAP, PKP2 and LAMA4. The mean level of obscurin mRNA was significantly greater and more variable in healthy donor samples than the DCM samples but did not correlate with OBSCN mutations. A single obscurin protein band was observed in human heart myofibrils with apparent mass 960 ± 60 kDa. The three samples with OBSCN mutations had significantly lower levels of obscurin immunoreactive material than DCM samples without OBSCN mutations (45±7, 48±3, and 72±6% of control level).Obscurin levels in DCM controls, donor heart and myectomy samples were the same.OBSCN mutations may result in the development of a DCM phenotype via haploinsufficiency. Mutations in the obscurin gene should be considered as a significant causal factor of DCM, alone or in concert with other mutations
Approximate treatment of electron Coulomb distortion in quasielastic (e,e') reactions
In this paper we address the adequacy of various approximate methods of
including Coulomb distortion effects in (e,e') reactions by comparing to an
exact treatment using Dirac-Coulomb distorted waves. In particular, we examine
approximate methods and analyses of (e,e') reactions developed by Traini et al.
using a high energy approximation of the distorted waves and phase shifts due
to Lenz and Rosenfelder. This approximation has been used in the separation of
longitudinal and transverse structure functions in a number of (e,e')
experiments including the newly published 208Pb(e,e') data from Saclay. We find
that the assumptions used by Traini and others are not valid for typical (e,e')
experiments on medium and heavy nuclei, and hence the extracted structure
functions based on this formalism are not reliable. We describe an improved
approximation which is also based on the high energy approximation of Lenz and
Rosenfelder and the analyses of Knoll and compare our results to the Saclay
data. At each step of our analyses we compare our approximate results to the
exact distorted wave results and can therefore quantify the errors made by our
approximations. We find that for light nuclei, we can get an excellent
treatment of Coulomb distortion effects on (e,e') reactions just by using a
good approximation to the distorted waves, but for medium and heavy nuclei
simple additional ad hoc factors need to be included. We describe an explicit
procedure for using our approximate analyses to extract so-called longitudinal
and transverse structure functions from (e,e') reactions in the quasielastic
region.Comment: 30 pages, 8 figures, 16 reference
An Analysis of Inclusive Education in Eastern Kentucky
A report submitted by James A. Knoll to the Research and Creative Productions Committee in April of 1997 on the results of a mail survey of educators in the elementary and middle schools in 30 school districts in Eastern Kentucky
Nucleate pool boiling in the long duration low gravity environment of the Space Shuttle
The results are presented of an experimental study of nucleate pool boiling performed in the low gravity environment of the space shuttle. Photographic observations of pool boiling in Freon 113 were obtained during the 'Tank Pressure Control Experiment,' flown on the Space Transportation System, STS-43 in August 1991. Nucleate boiling data from large (relative to bubble size) flat heating surfaces (0.1046 by 0.0742 m) was obtained at very low heat fluxes (0.22 to 1.19 kW/sq m). The system pressure and the bulk liquid subcooling varied in the range of 40 to 60 kPa and 3 to 5 C respectively. Thirty-eight boiling tests, each of 10-min duration for a given heat flux, were conducted. Measurements included the heater power, heater surface temperature, the liquid temperature and the system pressure as functions of heating time. Video data of the first 2 min of heating was recorded for each test. In some tests the video clearly shows the inception of boiling and the growth and departure of bubbles from the surface during the first 2 min of heating. In the absence of video data, the heater temperature variation during heating shows the inception of boiling and stable nucleate boiling. During the stable nucleate boiling, the wall superheat varied between 2.8 to 3.8 C for heat fluxes in the range of 0.95 to 1.19 kW/sq m. The wall superheat at the inception of boiling varied between 2 to 13 C
Coulomb Distortion Effects for (e,e'p) Reactions at High Electron Energy
We report a significant improvement of an approximate method of including
electron Coulomb distortion in electron induced reactions at momentum transfers
greater than the inverse of the size of the target nucleus. In particular, we
have found a new parametrization for the elastic electron scattering phase
shifts that works well at all electron energies greater than 300 . As an
illustration, we apply the improved approximation to the reaction
from medium and heavy nuclei. We use a relativistic ``single particle'' model
for as as applied to and to recently measured data
at CEBAF on to investigate Coulomb distortion effects while
examining the physics of the reaction.Comment: 14 pages, 3 figures, PRC submitte
- …